Computational Biophysics and Bioinformatics

Z. Zhang, V. Martiny, D. Lagorce, Y. Ikeguchi, E. Alexov, and others
Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual
2014
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Z. Zhang, V. Martiny, D. Lagorce, Y. Ikeguchi, E. Alexov, and M. A. Miteva
Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach
PLoS One, 9(10), e110884, 2014
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Z. Zhang, A. Pegg, Y. Ikeguchi, and E. Alexov
Enhancing Human Spermine Synthase Activity by Site Directed Mutations
Biophysical Journal, 104(2), 380a, 2013
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L. Wang, S. Witham, Z. Zhang, L. Li, M. E. Hodsdon, and E. Alexov
In silico investigation of pH-dependence of prolactin and human growth hormone binding to human prolactin receptor
Communications in computational physics, 13(1), 207, 2013
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Z. Zhang, S. Witham, M. Petukh, G. Moroy, M. Miteva, Y. Ikeguchi, and E. Alexov
A rational free energy-based approach to understanding and targeting disease-causing missense mutations
Journal of the American Medical Informatics Association, 20(4), 643-651, 2013
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Z. Zhang, Y. Zheng, M. Petukh, A. Pegg, Y. Ikeguchi, and E. Alexov
Enhancing human spermine synthase activity by engineered mutations
PLoS Comput Biol, 9(2), e1002924, 2013
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L. Wang, Z. Zhang, W. Rocchia, and E. Alexov
Using DelPhi capabilities to mimic protein’s conformational reorganization with amino acid specific dielectric constants
Communications in computational physics, 13(1), 13, 2013
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Z. Zhang, J. Norris, V. Kalscheuer, T. Wood, L. Wang, C. Schwartz, E. Alexov, and H. V. Esch
A Y328C missense mutation in spermine synthase causes a mild form of Snyder--Robinson syndrome
Human molecular genetics, 22(18), 3789-3797, 2013
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L. Li, C. Li, Z. Zhang, and E. Alexov
On the dielectric “constant” of proteins: smooth dielectric function for macromolecular modeling and its implementation in DelPhi
Journal of chemical theory and computation, 9(4), 2126-2136, 2013
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Z. Zhang, L. Wang, Y. Gao, J. Zhang, M. Zhenirovskyy, and E. Alexov
Predicting folding free energy changes upon single point mutations
Bioinformatics, 28(5), 664-671, 2012
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Z. Zhang, M. A. Miteva, L. Wang, and E. Alexov
Analyzing effects of naturally occurring missense mutations
Computational and mathematical methods in medicine, 2012, 2012
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L. Li, C. Li, S. Sarkar, J. Zhang, S. Witham, Z. Zhang, L. Wang, N. Smith, et al.
DelPhi: a comprehensive suite for DelPhi software and associated resources
BMC biophysics, 5(1), 1-11, 2012
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Z. Zhang, J. Norris, C. Schwartz, and E. Alexov
In Silico and In Vitro Investigations of the Mutability of Disease-Causing Missense Mutation Sites in
2011
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Z. Zhang, C. Schwartz, and E. Alexov
In Silico Investigation of Mutability of Spermine Synthase
Biophysical Journal, 100(3), 321a, 2011
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Z. Zhang, C. Schwatz, and E. Alexov
\backslashtextit \In silico\ investigation of molecular effects caused by missense mutations in creatine transporter protein
Bulletin of the American Physical Society, 56, 2011
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S. Witham, K. Talley, L. Wang, Z. Zhang, S. Sarkar, D. Gao, W. Yang, and E. Alexov
Developing hybrid approaches to predict pKa values of ionizable groups
Proteins: Structure, Function, and Bioinformatics, 79(12), 3389-3399, 2011
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R. C. Mitra, Z. Zhang, and E. Alexov
In silico modeling of pH-optimum of protein--protein binding
Proteins: Structure, Function, and Bioinformatics, 79(3), 925-936, 2011
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Z. Zhang, J. Norris, C. Schwartz, and E. Alexov
In silico and in vitro investigations of the mutability of disease-causing missense mutation sites in spermine synthase
PloS one, 6(5), e20373, 2011
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Z. Zhang, S. Witham, and E. Alexov
On the role of electrostatics in protein--protein interactions
Physical biology, 8(3), 035001, 2011
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Z. Zhang, S. Teng, L. Wang, C. E. Schwartz, and E. Alexov
Computational analysis of missense mutations causing Snyder-Robinson syndrome
Human mutation, 31(9), 1043-1049, 2010
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Computational Biophysics and Bioinformatics

Professor Emil Alexov Group

Journal Articles by Z. Zhang

Conference Papers