Delphi-PKA is a DelPhi-based C++ program, allowing to predict pKa's for ionizable groups in
RNA and DNA.
Unique approach stems from:
a) Use gaussian-based smooth function to mimic conformational changes
with ionization changes.
b) Calculate the electrostatic energy without defining molecular
For questions and help, email to firstname.lastname@example.org
Source code and installation files are on
DelPhiPKa Github Page.
User Manual can be found here.
If the use of DelPhiPKa results to a publication, please cite