Computational Biophysics and Bioinformatics

T. Kimmett, N. Smith, S. Witham, M. Petukh, S. Sarkar, and E. Alexov
ProBLM web server: protein and membrane placement and orientation package
Computational and mathematical methods in medicine, 2014, 2014
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L. Wang, S. Witham, Z. Zhang, L. Li, M. E. Hodsdon, and E. Alexov
In silico investigation of pH-dependence of prolactin and human growth hormone binding to human prolactin receptor
Communications in computational physics, 13(1), 207, 2013
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Z. Zhang, S. Witham, M. Petukh, G. Moroy, M. Miteva, Y. Ikeguchi, and E. Alexov
A rational free energy-based approach to understanding and targeting disease-causing missense mutations
Journal of the American Medical Informatics Association, 20(4), 643-651, 2013
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S. Sarkar, S. Witham, J. Zhang, M. Zhenirovskyy, W. Rocchia, and E. Alexov
DelPhi Web Server: A comprehensive online suite for electrostatic calculations of biological macromolecules and their complexes
Communications in computational physics, 13(1), 269, 2013
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S. Witham and E. Alexov
Modeling CLIC2-RyR Interactions and the Effect of Disease Causing Mutation
Biophysical Journal, 102(3), 456a, 2012
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N. Smith, S. Witham, S. Sarkar, J. Zhang, L. Li, C. Li, and E. Alexov
DelPhi web server v2: incorporating atomic-style geometrical figures into the computational protocol
Bioinformatics, 28(12), 1655-1657, 2012
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K. Takano, D. Liu, P. Tarpey, E. Gallant, A. Lam, S. Witham, E. Alexov, A. Chaubey, et al.
An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity
Human molecular genetics, 21(20), 4497-4507, 2012
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L. Li, C. Li, S. Sarkar, J. Zhang, S. Witham, Z. Zhang, L. Wang, N. Smith, et al.
DelPhi: a comprehensive suite for DelPhi software and associated resources
BMC biophysics, 5(1), 1-11, 2012
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S. Witham, K. Takano, C. Schwartz, and E. Alexov
In Silico Investigation of a Missense Mutation in CLIC2 Associated with Intellectual Disability
Biophysical Journal, 100(3), 611a, 2011
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S. Witham, K. Talley, L. Wang, Z. Zhang, S. Sarkar, D. Gao, W. Yang, and E. Alexov
Developing hybrid approaches to predict pKa values of ionizable groups
Proteins: Structure, Function, and Bioinformatics, 79(12), 3389-3399, 2011
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S. Witham, K. Takano, C. Schwartz, and E. Alexov
A missense mutation in CLIC2 associated with intellectual disability is predicted by in silico modeling to affect protein stability and dynamics
Proteins: Structure, Function, and Bioinformatics, 79(8), 2444-2454, 2011
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Z. Zhang, S. Witham, and E. Alexov
On the role of electrostatics in protein--protein interactions
Physical biology, 8(3), 035001, 2011
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Computational Biophysics and Bioinformatics

Professor Emil Alexov Group

Journal Articles by S. Witham

Conference Papers