Computational Biophysics and Bioinformatics

I. Getov, M. Petukh, and E. Alexov
Predicting folding free energy changes caused by single point mutations via combined usage of MM-PBSA method and biophysical characteristics
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015
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S. V. Tavtigian
Shotgun Approach to Functional Annotation of Genes
Human Mutation, 36(2), v-v, 2015
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E. Alexov
Navigating through genomics data to deliver testable predictions
Human Mutation, 36(2), v-v, 2015
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M. Petukh, J. Morrison, M. Li, A. Panchenko, and E. Alexov
SAMBE: The New Webserver for Predicting the Effect of nssNP on the Protein-Protein Binding Free Energy
Biophysical Journal, 108(2), 157a-158a, 2015
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M. Petukh, M. Zhang, and E. Alexov
Statistical investigation of surface bound ions and further development of BION server to include p H and salt dependence
Journal of computational chemistry, 36(32), 2381-2393, 2015
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M. May, K.-S. Hwang, J. Miles, C. Williams, T. Niranjan, S. G. Kahler, P. Chiurazzi, K. Steindl, et al.
ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons
Human molecular genetics, 24(17), 4848-4861, 2015
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T. G. Kucukkal and E. Alexov
Structural, dynamical, and energetical consequences of Rett syndrome mutation R133C in MeCP2
Computational and mathematical methods in medicine, 2015, 2015
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T. G. Kucukkal, Y. Yang, O. Uvarov, W. Cao, and E. Alexov
Impact of rett syndrome mutations on MeCP2 MBD stability
Biochemistry, 54(41), 6357-6368, 2015
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Y. Peng, J. Suryadi, Y. Yang, T. G. Kucukkal, W. Cao, and E. Alexov
Mutations in the KDM5C ARID domain and their plausible association with syndromic Claes-Jensen-Type disease
International journal of molecular sciences, 16(11), 27270-27287, 2015
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L. Li, L. Wang, and E. Alexov
On the energy components governing molecular recognition in the framework of continuum approaches
Frontiers in molecular biosciences, 2, 5, 2015
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M. Petukh, M. Li, and E. Alexov
Predicting binding free energy change caused by point mutations with knowledge-modified MM/PBSA method
PLoS computational biology, 11(7), e1004276, 2015
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L. Wang, L. Li, and E. Alexov
pKa predictions for proteins, RNA s, and DNA s with the Gaussian dielectric function using DelPhi pKa
Proteins: Structure, Function, and Bioinformatics, 83(12), 2186-2197, 2015
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M. Petukh, T. G. Kucukkal, and E. Alexov
On human disease-causing amino acid variants: Statistical study of sequence and structural patterns
Human mutation, 36(5), 524-534, 2015
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T. G. Kucukkal, M. Petukh, L. Li, and E. Alexov
Structural and physico-chemical effects of disease and non-disease nsSNPs on proteins
Current opinion in structural biology, 32, 18-24, 2015
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Computational Biophysics and Bioinformatics

Professor Emil Alexov Group

2015