TY - JOUR T1 - Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual AU - Zhang, Z. AU - Martiny, V. AU - Lagorce, D. AU - Ikeguchi, Y. AU - Alexov, E. AU - others, PY - 2014 ER - TY - CHAP T1 - Modeling ensemble-averaged electrostatics with smooth Gaussian-based dielectric function AU - Li, L. AU - Smith, N. AU - Alexov, E. TI - ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY PY - 2014 VL - 248 ER - TY - JOUR T1 - Molecular mechanisms underlying pathogenic missense mutations AU - Wu, B. AU - Eggert, J. AU - Alexov, E. JO - eLS PY - 2014 PB - American Cancer Society ER - TY - JOUR T1 - On the electrostatic properties of homodimeric proteins AU - Campbell, B. AU - Petukh, M. AU - Alexov, E. AU - Li, C. JO - Journal of Theoretical and Computational Chemistry PY - 2014 PB - World Scientific Publishing Company VL - 13 IS - 3 SP - 1440007 EP - 1440007 ER - TY - JOUR T1 - Ion binding to biological macromolecules AU - Petukh, M. AU - Alexov, E. JO - Asian journal of physics: an international quarterly research journal PY - 2014 PB - NIH Public Access VL - 23 IS - 5 SP - 735 EP - 735 ER - TY - JOUR T1 - Structural and energetic determinants of tyrosylprotein sulfotransferase sulfation specificity AU - Nedumpully-Govindan, P. AU - Li, L. AU - Alexov, E. G. AU - Blenner, M. A. AU - Ding, F. JO - Bioinformatics PY - 2014 PB - Oxford University Press VL - 30 IS - 16 SP - 2302 EP - 2309 ER - TY - JOUR T1 - Advances in human biology: combining genetics and molecular biophysics to pave the way for personalized diagnostics and medicine AU - Alexov, E. JO - Advances in Biology PY - 2014 PB - Hindawi VL - 2014 ER - TY - JOUR T1 - Chronic beryllium disease: revealing the role of beryllium ion and small peptides binding to HLA-DP2 AU - Petukh, M. AU - Wu, B. AU - Stefl, S. AU - Smith, N. AU - Hyde-Volpe, D. AU - Wang, L. AU - Alexov, E. JO - PLoS One PY - 2014 PB - Public Library of Science VL - 9 IS - 11 SP - e111604 EP - e111604 ER - TY - JOUR T1 - ProBLM web server: protein and membrane placement and orientation package AU - Kimmett, T. AU - Smith, N. AU - Witham, S. AU - Petukh, M. AU - Sarkar, S. AU - Alexov, E. JO - Computational and mathematical methods in medicine PY - 2014 PB - Hindawi VL - 2014 ER - TY - JOUR T1 - Modeling the electrostatic potential of asymmetric lipopolysaccharide membranes: the MEMPOT algorithm implemented in DelPhi AU - Dias, R. P. AU - Li, L. AU - Soares, T. A. AU - Alexov, E. JO - Journal of computational chemistry PY - 2014 VL - 35 IS - 19 SP - 1418 EP - 1429 ER - TY - JOUR T1 - On the modeling of polar component of solvation energy using smooth Gaussian-based dielectric function AU - Li, L. AU - Li, C. AU - Alexov, E. JO - Journal of Theoretical and Computational Chemistry PY - 2014 PB - World Scientific Publishing Company VL - 13 IS - 3 SP - 1440002 EP - 1440002 ER - TY - JOUR T1 - Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach AU - Zhang, Z. AU - Martiny, V. AU - Lagorce, D. AU - Ikeguchi, Y. AU - Alexov, E. AU - Miteva, M. A. JO - PLoS One PY - 2014 PB - Public Library of Science VL - 9 IS - 10 SP - e110884 EP - e110884 ER - TY - JOUR T1 - A novel p. Leu (381) Phe mutation in presenilin 1 is associated with very early onset and unusually fast progressing dementia as well as lysosomal inclusions typically seen in Kufs disease AU - Dolzhanskaya, N. AU - Gonzalez, M. A. AU - Sperziani, F. AU - Stefl, S. AU - Messing, J. AU - Wen, G. Y. AU - Alexov, E. AU - Zuchner, S. AU - Velinov, M. JO - Journal of Alzheimer's Disease PY - 2014 PB - IOS Press VL - 39 IS - 1 SP - 23 EP - 27 ER - TY - JOUR T1 - Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics AU - Kucukkal, T. G. AU - Yang, Y. AU - Chapman, S. C. AU - Cao, W. AU - Alexov, E. JO - International journal of molecular sciences PY - 2014 PB - Multidisciplinary Digital Publishing Institute VL - 15 IS - 6 SP - 9670 EP - 9717 ER - TY - JOUR T1 - Predicting the impact of missense mutations on protein--protein binding affinity AU - Li, M. AU - Petukh, M. AU - Alexov, E. AU - Panchenko, A. R. JO - Journal of chemical theory and computation PY - 2014 PB - American Chemical Society VL - 10 IS - 4 SP - 1770 EP - 1780 ER - TY - JOUR T1 - A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt \& pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation AU - Boccuto, L. AU - Aoki, K. AU - Flanagan-Steet, H. AU - Chen, C.-F. AU - Fan, X. AU - Bartel, F. AU - Petukh, M. AU - Pittman, A. AU - Saul, R. AU - Chaubey, A. AU - others, JO - Human molecular genetics PY - 2014 PB - Oxford University Press VL - 23 IS - 2 SP - 418 EP - 433 ER -