TY - JOUR T1 - Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual AU - Zhang, Z. AU - Martiny, V. AU - Lagorce, D. AU - Ikeguchi, Y. AU - Alexov, E. AU - others, PY - 2014 ER - TY - JOUR T1 - Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach AU - Zhang, Z. AU - Martiny, V. AU - Lagorce, D. AU - Ikeguchi, Y. AU - Alexov, E. AU - Miteva, M. A. JO - PLoS One PY - 2014 PB - Public Library of Science VL - 9 IS - 10 SP - e110884 EP - e110884 ER - TY - JOUR T1 - Enhancing Human Spermine Synthase Activity by Site Directed Mutations AU - Zhang, Z. AU - Pegg, A. AU - Ikeguchi, Y. AU - Alexov, E. JO - Biophysical Journal PY - 2013 PB - Elsevier VL - 104 IS - 2 SP - 380a EP - 380a ER - TY - JOUR T1 - A rational free energy-based approach to understanding and targeting disease-causing missense mutations AU - Zhang, Z. AU - Witham, S. AU - Petukh, M. AU - Moroy, G. AU - Miteva, M. AU - Ikeguchi, Y. AU - Alexov, E. JO - Journal of the American Medical Informatics Association PY - 2013 PB - BMJ Publishing Group BMA House, Tavistock Square, London, WC1H 9JR VL - 20 IS - 4 SP - 643 EP - 651 ER - TY - JOUR T1 - Enhancing human spermine synthase activity by engineered mutations AU - Zhang, Z. AU - Zheng, Y. AU - Petukh, M. AU - Pegg, A. AU - Ikeguchi, Y. AU - Alexov, E. JO - PLoS Comput Biol PY - 2013 PB - Public Library of Science VL - 9 IS - 2 SP - e1002924 EP - e1002924 ER -