R. Aprigliano, S. Bradamante, B. Mihaljevic, W. Wang, S. L. F. Martin, D. L. Bordin, M. Bosshard, N. P. Montaldo, Y. Peng, E. Alexov, and others. Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities. Cell Reports Medicine, Cold Spring Harbor Laboratory, volume 2, pages 100240, April 2021. E. Alexov and others. An Ensemble Approach to Predict the Pathogenicity of Synonymous Variants. Genes, volume 11, issue 9, 2020. Y.-R. Lee, K. Khan, K. Armfield-Uhas, S. Srikanth, N. A. Thompson, M. Pardo, L. Yu, J. W. Norris, Y. Peng, K. W. Gripp, and others. Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy. Nature communications, Nature Publishing Group, volume 11, issue 1, pages 1-17, 2020. C. Li, Z. Jia, A. Chakravorty, S. Pahari, Y. Peng, S. Basu, M. Koirala, S. K. Panday, M. Petukh, L. Li, and others. DelPhi suite: New developments and review of functionalities. Journal of computational chemistry, John Wiley \& Sons, Inc. Hoboken, USA, volume 40, issue 28, pages 2502-2508, 2019. C. J. Spellicy, Y. Peng, L. Olewiler, S. S. Cathey, R. C. Rogers, D. Bartholomew, J. Johnson, E. Alexov, J. A. Lee, M. J. Friez, and others. Three additional patients with EED-associated overgrowth: potential mutation hotspots identified? Journal of human genetics, Nature Publishing Group, volume 64, issue 6, pages 561-572, 2019. C. J. Spellicy, J. Norris, R. Bend, C. Bupp, P. Mester, T. Reynolds, J. Dean, Y. Peng, E. Alexov, C. E. Schwartz, and others. Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects. European Journal of Human Genetics, Nature Publishing Group, volume 26, issue 3, pages 420-427, 2018. K. Vaidyanathan, T. Niranjan, N. Selvan, C. F. Teo, M. May, S. Patel, B. Weatherly, C. Skinner, J. Opitz, J. Carey, and others. Identification and characterization of a missense mutation in the O-linked $\beta$-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability. Journal of Biological Chemistry, Elsevier, volume 292, issue 21, pages 8948-8963, 2017. N. Selvan, K. Vaidyanathan, S. George, T. Niranjan, C. F. Teo, M. May, S. Patel, B. Weatherly, J. Opitz, J. Carey, and others. Identification and Characterization of Multiple Missense Mutations in the O-GlcNAc transferase gene that are causal for X-linked Intellectual Disability. GLYCOBIOLOGY, volume 27, issue 12, pages 1187-1187, 2017. K. Vaidyanathan, T. Niranjan, N. Selvan, C. F. Teo, M. May, S. Patel, B. Weatherly, C. Skinner, J. Opitz, J. Carey, and others. Identification and characterization of a missense mutation in the O-GlcNAc transferase gene that segregates with X-linked intellectual disability. J. Biol. Chem, volume 292, pages 8948-8963, 2017. M. May, K.-S. Hwang, J. Miles, C. Williams, T. Niranjan, S. G. Kahler, P. Chiurazzi, K. Steindl, P. J. V. D. Spek, S. Swagemakers, and others. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons. Human molecular genetics, Oxford University Press, volume 24, issue 17, pages 4848-4861, 2015. Z. Zhang, V. Martiny, D. Lagorce, Y. Ikeguchi, E. Alexov, and others. Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual. 2014. L. Boccuto, K. Aoki, H. Flanagan-Steet, C.-F. Chen, X. Fan, F. Bartel, M. Petukh, A. Pittman, R. Saul, A. Chaubey, and others. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt \& pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation. Human molecular genetics, Oxford University Press, volume 23, issue 2, pages 418-433, 2014. K. Vaidyanathan, T. Niranjan, M. May, R. Rose, C. F. Teo, S. Prabakaran, R. Bridger, E. Alexov, T. Wang, C. Schwartz, and others. Characterizing a missense mutation in O-GlcNAc transferase that segregates with disease in a family with X-linked Intellectual Disability. GLYCOBIOLOGY, volume 23, issue 11, pages 1334-1335, 2013. Z. Zhang, V. Martiny, D. Lagorce, E. Alexov, M. Miteva, and others. Snyder-Robinson Syndrome: Rescuing the Disease-Causing Effect of G56S mutant by Small Molecule Binding. APS March Meeting Abstracts, volume 2013, pages G45-005, 2013. K. Takano, D. Liu, P. Tarpey, E. Gallant, A. Lam, S. Witham, E. Alexov, A. Chaubey, R. E. Stevenson, C. E. Schwartz, and others. An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity. Human molecular genetics, Oxford University Press, volume 21, issue 20, pages 4497-4507, 2012. E. Alexov, E. L. Mehler, N. Baker, A. M. Baptista, Y. Huang, F. Milletti, J. E. Nielsen, D. Farrell, T. Carstensen, M. H. Olsson, and others. Progress in the prediction of pKa values in proteins. Proteins: structure, function, and bioinformatics, Wiley Subscription Services, Inc., A Wiley Company Hoboken, volume 79, issue 12, pages 3260-3275, 2011. A. Pittman, R. Saul, A. Chaubey, E. Alexov, M. Tiemeyer, R. Steet, C. Schwartz, M. B\'en\'eteau, J. Ricci, V. Desquiret-Dumas, and others. PMCID: PMC2695060. Int Immunol, volume 22, issue 7, pages 593-603, 2010. N. Tanaka, S. Nakao, J. Chatellier, Y. Tani, T. Tada, S. Kunugi, F. Sicilia, B. Mattei, F. Cervone, D. Bellincampi, and others. Proteins and Proteomics Cumulative Contents. Biochimica et Biophysica Acta, volume 1748, pages 233-234, 2005. D. Petrey, Z. Xiang, C. L. Tang, L. Xie, M. Gimpelev, T. Mitros, C. S. Soto, S. Goldsmith-Fischman, A. Kernytsky, A. Schlessinger, and others. Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling. Proteins: Structure, Function, and Bioinformatics, Wiley Subscription Services, Inc., A Wiley Company Hoboken, volume 53, issue 6, pages 430-435, 2003. V. Alexandrov, E. G. Alexov, M. Andrec, A. Apostolico, A. Bhattacharya, D. J. Brooks, R. L. Cai, A. Colasanti, W. Ding, P. Du, and others. Participant List. Proceedings of the Tsukuba Global Carbon Cycle Workshop--Global Environment Tsukuba'95: February 1-3, 1995, Tsukuba, Japan, pages 169, 1995.