Clemson Robot created by Brandon Campbell, with Protein Nano-Object
Integrator package developed by Nick Smith. The potential distribution was
calculated with parallelized DelPhi developed by Chuan Li and the movie
was created by Lin Li. Webpage design by Taylor Kimmett.
Atomic-style robot holding in its hand barnase-barstar complex. Potential map calculated with DelPhi.
The research in the lab focuses on
computational modeling of biological
macromolecules and their
assemblages and predicting
biophysical quantities associated
with them. The main focus of the lab
is the development and maintenance of the
popular software package DelPhi, which calculates electrostatic potential and energies
of systems comprised of biological macromolecules. In addition,
we are interested in modeling
mutations, pKa's of amino acids and
nucleic groups and pH-dependence
of stability and binding. In parallel
with in silico modeling, the lab
actively collaborates with
experimetalists to better understand
molecular mechanisms of biological
reactions and interactions. The
combination of the methods of
Computational Biophysics and
Bioinformatics with experimental
results is an essential approach
utilized in our research.
Visit this page to see a better video demonstrating the Clemson Robot and DelPhi's capabilities.