Clemson Robot

Atomic-style robot holding barnase-barstar complex.

Created by Brandon Campbell, ProNOI package developed by Nick Smith. Potential distribution calculated with parallelized DelPhi developed by Chuan Li. Movie created by Lin Li.

The research in the lab focuses on computational modeling of biological macromolecules and their assemblages as well as predicting biophysical quantities associated with them. One of the primary roles of the lab is to develop and maintain the popular software package DelPhi, which calculates electrostatic potentials and energies of systems comprised of biological macromolecules. We are also interested in modeling disease-causing missense mutations, pKa's of amino acids and nucleic groups, and pH-dependence of stability and binding.